Publications

David J. Dorer, Ph.D.

Impact of Dose Intensity of Ponatinib on Selected Adverse Events: Multivariate Analyses from a Pooled Population of Clinical Trial Patients.   Dorer DJ, Knickerbocker RK, Baccarani M, Cortes JE, Hochhaus A, Talpaz M, Haluska FG,  Leuk Res, 2016, 48:84-91,   PMID:  27505637     pdf

Activity and Safety of Brigatinib in ALK-Rearranged Non-Small-Cell Lung Cancer and Other Malignancies: a Single-Arm, Open-Label, Phase 1/2 Trial.   Gettinger SN, Bazhenova LA, Langer CJ, Salgia R, Gold KA, Rosell R, Shaw AT, Weiss GJ, Tugnait M, Narasimhan NI, Dorer DJ, Kerstein D, Rivera VM, Clackson T, Haluska FG, Camidge DR,   Lancet Oncol, 2016, 17(12):1683-1696,   PMID:  27836716

Mortality and Vascular Events Among Elderly Patients with Chronic Myeloid Leukemia: A Retrospective Analysis of Linked SEER-Medicare Data.   Lang K, McGarry LJ, Huang H, Dorer D, Kaufman E, Knopf K,   Clin Lymphoma Myeloma Leuk, 2016, 275-285.e1,   PMID:  27013180     pdf

Analysis of the Potential Effect of Ponatinib on the QTc Interval in Patients with Refractory Hematological Malignancies.   Sonnichsen D, Dorer DJ, Cortes J, Talpaz M, Deininger MW, Shah NP, Kantarjian HM, Bixby D, Mauro MJ, Flinn IW, Litwin J, Turner CD, Haluska FG,   Cancer Chemother Pharmacol, 2013, 71(6):1599-607,   PMID:  23609479     pdf

The Problem of the Placebo Response in Clinical Trials for Psychiatric Disorders: Culprits, Possible Remedies, and a Novel Study Design Approach.   Fava M, Evins, AE, Dorer DJ, Schoenfeld DA,   Psychotherapy and Psychosomatics, 2003, 72 115-127,   PMID:  12707478

Recovery and Relapse in Anorexia and Bulimia Nervosa: A 7.5 Year Follow-Up Study.   Herzog DB, Dorer DJ, Keel PK, Selwyn SE, Ekeblad ER, Flores AT, Greenwood DN, Burwell RA, Keller MB,   JAACAP, 1999, 38: 829-837,   PMID:  10405500

Clinical Outcomes of Near Term Infants.   Wang ML, Dorer DJ, Fleming MP, Catlin EA,   Pediatrics, 2004, 114(2) 372-376,   PMID:  15286219

SSRI and Statin Use Increased the Risk for Vasospasm after Subarachnoid Hemorrhage.   Singhal AB, Topcuoglu MA, Dorer DJ, Ogilvy CS, Carter BS, Koroshetz WJ,   Neurology, 2005, 34(6):1008-1013,   PMID:  15781818

31P Nuclear Magnetic Resonance Spectroscopy Findings in Bipolar Illness: A Meta-Analysis.   Yildiz A, Sachs GS, Dorer DJ, Renshaw PF,   Psychiatry Research Neuroimaging, 2001, 106:181-191,   PMID:  11382540

Relationship Between Force and Size in Human Single Muscle Fibres.   Krivickas, LS, Dorer DJ, Ochala, J, Frontera, WR,   Experimental Physiology, 2011, 96(5):539-47,   PMID:  21317219     pdf

Enteral Omega-3 Fatty Acid, Gamma-Linolenic Acid, and Antioxidant Supplementation in Acute Lung Injury.   Rice TW, Wheeler AP, Thompson BT, deBoisblanc BP, Steingrub J, Rock P, NIH NHLBI Acute Respiratory Distress Syndrome Network of Investigators (network member),   JAMA, 2011, 306(14):1574-81,   PMID:  21976613     pdf

Randomized Placebo-Controlled Clinical Trial of Aerosolized Beta-2 Agonist for Treatment of Acute Lung Injury.   National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network, Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, MacIntyre N, Moss M, Schoenfeld D, Steingrub J, Thompson BT, (network member),   Am J Respir Crit Care Med, 2011, 184(5):561-8,   PMID:  21562125     pdf

The Accreditation Council for Graduate Medical Educations Limits on Residents Work Hours and Patient Safety, a Study of Resident Experiences and Perceptions Before and after Hours Reductions.   Jagsi R, Weinstein DF, Shapiro J,Kitch BT, Dorer D, Weissman JS,   Archive Internal Medicine, 2009, 168(5):493-500,   PMID:  18332295

Determinants of Carotid Endartectomy Anatomic Durability: Effects of Serum Lipids and Lipid-Lowering Drugs.   LaMurglia GM, Stoner MC, Brewster DC, Watkins MT, Juhola KL, Kwolek C, Dorer DJ, Cambria RP,   J Vasc Surg, 2005, 41(5):762-768,   PMID:  15886657     pdf

Blood Group, Immunity, and Risk of Infection with Vibrio Cholerae in an Area of Endemicity.   Harris JB, Khan AI, LaRocque RC, Dorer DJ, Chowdhury F, Faruque ASG, Sack DA, Ryan ET, Qadri F, Calderwood SB,   Infection and Immunity, 2005, 73(11):7422-7427,   PMID:  16239542     pdf

Diagnostic Crossover in Anorexia Nervosa and Bulimia Nervosa: Implications for DSM-V.   Eddy KT, Dorer DJ, Franko DL, Tahilani K, Thompson-Brenner, Herzon DB,   American Journal of Psychiatry, 2008, 165(2):245-250,   PMID:  18198267     pdf

Evaluation of the Effect of Multiple Doses of Rifampin on the Pharmacokinetics and Safety of Ponatinib in Healthy Subjects.   Narasimhan NI, Dorer DJ, Davis J, Turner CD, Sonnichsen D,   Clin Pharmacol Drug Dev, 2015, 354-360,   PMID:  27137144

Evaluation of Pharmacokinetics and Safety of Ponatinib in Subjects with Chronic Hepatic Impairment and Matched Healthy Subjects.   Narasimhan NI, Dorer DJ, Davis J, Turner CD, Marbury TC, Sonnichsen D,   Cancer Chemother Pharmacol, 2014, 74(2):341-348,   PMID:  24934866

Personality Pathology and Substance Abuse in Eating Disorders: a Longitudinal Study.   Thompson-Brenner H, Eddy KT, Franko DL, Dorer D, Vashchenko M, Herzog D,   International Journal of Eating Disorders, 2008, 41(3):203-208,   PMID:  18027859

Evaluation of the Effect of Multiple Doses of Lansoprazole on the Pharmacokinetics and Safety of Ponatinib in Healthy Subjects.   Narasimhan NI, Dorer DJ, Davis J, Turner CD, Sonnichsen D,   Clin Drug Investig, 2014, 34(10):723-729,   PMID:  25145453

Effects of Ketoconazole on the Pharmacokinetics of Ponatinib in Healthy Subjects.   Narasimhan NI, Dorer DJ, Niland K, Haluska F, Sonnichsen D,   J Clin Pharmacol, 2013, 53(9):974-981,   PMID:  23801357     pdf

Effects of Food on the Pharmacokinetics of Ponatinib in Healthy Subjects.   Narasimhan NI, Dorer DJ, Niland K, Haluska F, Sonnichsen D,   J Clin Pharm Ther, 2013, 38(6):440-4,   PMID:  23888935     pdf

Interactions Between Eating Disorders and Drug Abuse.   Franko DL, Dorer DJ, Keel PK, Jackson S, Manzo MP, Herzog DB,   Journal of Nervous and Mental Disease, 2008, 196(7):556-561,   PMID:  18626296

Single Skeletal Muscle Fiber Elastic and Contractile Characteristics in Young and Older Men.   Ochala J, Frontera WR, Dorer DJ, Van Hoecke J, Krivacks LS,   J Gerontol A Biol Sci Med Sci, 2007, 62(4):375-381,   PMID:  17452730

Economic Evaluation of Interactive Teledermatology Compared with Conventional Care.   Armstrong, AW, Dorer DJ, Lugn NE, Kvedar JC,   Telemed J E Health, 2007, 13(2):91-9,   PMID:  17489695

Should Bulimia Nervosa be Subtyped by History of Anorexia Nervosa? a Longitudinal Validation.   Eddy KT, Dorer DJ, Franko DL, Tahilani K, Thompson-Brenner H, Herzog DB,   Int J Eat Disord, 2007, 40 Suppl:S67-71,   PMID:  17610249

Point Prevalence of Bulimia Nervosa in 1982, 1992, 2002.   Keel PK, Heatherton TF, Dorer DJ, Joiner TE, Zalta AK,   Psychological Medicine, 2006, 36(1):119-127,   PMID:  16202192

Sex Differences in Single Muscle Fiber Power in Older Adults.   Krivickas LS, Fielding RA, Murray A, Callahan D, Johansson A, Dorer DJ, Frontera WR,   Med Sci Sports Exerc, 2006, 38(1):57-63,   PMID:  16394954

The Relationship Between Human Semen Characteristics and Sperm Apoptosis: a Pilot Study.   Chen Z, Hauser R, Trbovich AM, Shifren JL, Dorer DJ, Godfrey-Bailey L, Singh NP,   J Androl, 2006, 27(1):112-120,   PMID:  16400087

Routine Repeat CT for Minimal Head Injury is Unnecessary.   Velmahos GC, Gervasini A, Petrovick L, Dorer DJ, Doran ME, Spaniolas K, Alam HB, DeMoya M,Borges LF, Conn AK,   J of Trauma Injury, Infection and Critical Care, 2006, 60:494-501,   PMID:  16531845

Drug Abuse in Women with Eating Disorders.   Herzog DB, Franko DL, Dorer DJ, Keel PK, Jackson S, Manzo MP,   International Journal of Eating Disorders, 2006, 39(5):364-368,   PMID:  16565976

Single Skeletal Muscle Fiber Behavior after a Quick Stretch in Young and Older Men: a Possible Explanation of the Relative Preservation of Eccentric Force in Old Age.   Ochala J, Dorer DJ, Frontera WR, Krivickas LS,   Pfugers Arch, 2006, 452(4):464-470,   PMID:  16622703

Geometric Determinants of Functional Tricuspid Regurgitation: Insights from 3 Dimensional Echocardiography.   Ton-Nu TT, Levine RA, Handschumacher MD, Dorer DJ, Yosefy C, Fan D,Hua L, Jiang L, Hung J,   Circulation, 2006, 11:114(2):143-149,   PMID:  16818811

Predictiors for the Development of Elevated Anti-Heparin/Platelet Factor 4 Antibody Titers in Patients Undergoing Cardiac Catherization.   Yeh RW, Evertt BM, Foo SY, Dorer DJ, Laposata M, Van Cott EM, Jang IK,   Am J Cardio, 2006, 98(3):419-421,   PMID:  16860036

The Educational Impact of ACGME Limits on Resident and Fellow Duty Hours: A Pre-Post Survey Study.   Jagsi R, Shapiro J, Weissman JS, Dorer DJ, Weinstein DF,   Acad Med, 2006, 81(12):1059-1068,   PMID:  17122470

How Do Eating Disorders and Alcohol Use Disorders Influence Each Other?.   Franko, DL, Dorer, DJ, Keel, PK, Jackson, S, Manzo, MP, & Herzog, DB,   International Journal of Eating Disorders, 2005, 38(3):200-207,   PMID:  16216020

Infantile Spasms and Intellectual Outcomes in Children with Tuberous Sclerosis Complex.   Goh S,Kwiatkowski DJ, Dorer DJ, Thiele EA,   Neurology, 2005, 65(2):235-238,   PMID:  16043792

Post-Remission Predictors of Relapse in Eating Disorders.   Keel PK, Dorer DJ, Franko DL, Jackson SC, Herzog DB,   American Journal of Psychiatry, 2005, 62(12):2263-2268,   PMID:  16330589

Preservation of Renal Function with Surgical Revascularization in Patients with Atherosclerotic Renovascular Disease.   Marone LK, Clouse WD, Dorer DJ, Brewster DC, LaMuraglia GM, Watkins MT, Kwolek CJ, Cambria RP,   J Vasc Surg, 2004, 39(2) 322-329,   PMID:  14743131     pdf

Diagnostic Errors after Inferior Petrosal Sinus Sampling.   Swearingen B, Katznelson L, Miller K, Grinspoon S, Waltman A, Dorer DJ, Klibanski A, Biller BM,   J Clin Endocrinol Metab, 2004, 89(8) 3752-3763,   PMID:  15292301

Carotid Endarterectomy at the Millennium: What Interventional Therapy Must Match.   LaMuraglia GM, Brewster DC, Moncure AD, Dorer DJ, Stoner MC, Trehan SC, Drynnibd Ecm Abbott WM, Cabria RP,   Ann Surg, 2004, 240(3) 535-544,   PMID:  15319725     pdf

What Predicts Suicide Attempts in Women with Eating Disorders?.   Franko DL, Keel PK, Dorer DJ, Blais M, Delinsky SS, Eddy KT, Charat V, Renn R, Herzog DB,   Psychological Medicine, 2004, :34(5):843-853,   PMID:  15500305

Predictors of Mortality in Eating Disorders.   Keel PK, Dorer DJ, Eddy KT, Franko D, Charatan D, Herzog DB,   Archives of General Psychiatry, 2003, 60:179-183,   PMID:  12578435

Late Aortic and Graft-Related Events after Thoracoabdominal Aneurysm Repair.   Clouse WD, Marone LK, Davison JK, Dorer DJ, Brewster DC,Lamuraglia GM, Cambria RP,   J Vasc Surg, 2003, 37(2):254-261,   PMID:  12563193     pdf

A Longitudinal Comparison of Anorexia Nervosa Subtypes.   Eddy KT, Keel PK, Dorer DJ, Delinsky SS, Franko DL, Herzog DB,   Intl J Eat Dis, 2002, 31:191-201,   PMID:  11920980

Predictors of Treatment Utilization in Women with Anorexia and Bulimia Nervosa.   Keel PK, Dorer DJ, Eddy KT, Selwyn SE, Franko DL, Blais MA, Keller MB, Herzog DB,   Am J Psychiatry, 2002, 159:140-2,   PMID:  11772705

Thoracoabdominal Aneurysm Repair: Results with 337 Operations Performed Over a 15-Year Interval.   Cambria, RP,Clouse WD, Davison JK, Dunn PF, Corey M, Dorer D,   Ann Surgery, 2002, 236:471-479,   PMID:  12368676     pdf

Mortality in Eating Disorders.   Herzog DB, Greenwood DN, Dorer DJ, Flores AT, Ekeblad ER, Richards A, Blais MA,   Intl J Eat Dis, 2000, 28: 20-26,   PMID:  10800010

A Crossover Study of Lecithin for Tardive Dyskinesia.   Gelenberg AJ, Dorer DJ, Wojcik J, Falk WE, Brotman AW, Leahy LM,   J Clin Psychiatry, 1990, 51: 149-153,   PMID:  2182613

Maternal Expressed Emotion and Parental Affective Disorder: Risk for Childhood Depressive Disorder, Substance Abuse, or Conduct Disorder.   Schwartz CE, Dorer DJ, Beardslee WR, Lavori PW, Keller MB,   J Psychiatric Res, 1990, 24: 231-250,   PMID:  2266512

Evaluation of the 11CO2 Positron Emission Tomographic Method for Measuring Brain pH, II. Quantitative pH Mapping in Patients with Ischemic Cerbrovascular Diseases.   Senda M, Alpert NM, Mackey BC, Buxton RB, Correia JA, Weise SB, Ackerman RH, Dorer DJ, Buonanno FS,   J Cerebral Blood Flow and Metabolism, 1989, 9: 859-873,   PMID:  2511212

Psychiatric Disorder in Adolescent Offspring of Parents with Affective Disorder in a Non-Referred Sample.   Beardslee WR, Keller MB, Lavori PW, Klerman GL, Dorer DJ, Samuelson H,   J Affective Dis, 1988, 15: 313-332,   PMID:  2975303

Affective Disorders in Childhood: Separating the Familial Component of Risk from Individual Characteristics of Children.   Lavori PW, Keller MB, Beardslee WR, Dorer DJ,   J Affective Dis, 1988, 15: 303-311,   PMID:  2975302

Patients Treated with Psychodynamic Psychotherapy by Residents and Massachusetts General Hospital.   Brotman AW, Pascarzi GA, Keller MB, Dorer DJ, Eisenthal S,   J Psychiatric Education, 1987, 11: 233-242,   Springer

Impact of Severity and Chronicity of Parental Affective Illness on Adaptive Functioning and Psychopathology in Children.   Keller MB, Beardslee WR, Dorer DJ, Lavori PW, Samuelson H, Klerman GL,   Archives of General Psychiatry, 1986, 43: 930-937,   PMID:  3753160

Stochastic Systems: The Mathematics of Filtering and Identification and Applications.   Caines PE, Dorer DJ,   Proceedings of the NATO-ASI Workshop, Les Arc France, Reidel Publishing, 1980, NATO Advanced Study Institutes Series v78,   Springer Books